Nebido injection is highly popular in the bodybuilding industry as well as among fitness enthusiasts. Apart from this, it plays a crucial role in testosterone replacement therapy in men suffering from low or lack of natural testosterone (hypogonadism). So, here’s everything you need to know about Nebido injection (testosterone undecanoate). Also, here you can learn how it works, who are the suitable candidates, who shouldn’t use it, and what are the potential side effects as well. So here we go.
Use of Nebido?
Nebido is used in men for Testosterone replacement therapy for treating low or no production of natural testosterone (hypogonadism). Nebido is injected into a muscle in the user’s body where it gets stored. And then it gradually releases.
Testosterone deficiency is assured by two separate blood testosterone measurements. And this also comes with clinical symptoms including impotence, tiredness, infertility, low sex drive, depressive moods, and bone loss caused by testosterone deficiency.
How Nebido works
Nebido injection comprises the active ingredient testosterone undecanoate, an ester of the male hormone testosterone that naturally occurs in the body. Testosterone is an androgen that is produced by the testicles. This is the main hormone vital for normal growth and maintenance of the male sex organs and male sexual traits (https://www.netdoctor.co.uk/medicines/a7594/nebido-injection-testosterone/).
The natural testosterone production is regulated by another range of hormones named gonadotrophins. These are released from the pituitary gland situated in the brain. During adult life, testosterone is vital for sperm production, in maintaining sex drive, sustaining erectile potency, etc. The other factors are the functioning of the prostate gland along with other reproductive structures.
It also has functions in the skeleton, kidney, skin, muscles, liver, bone marrow, and central nervous system.
Nebido injection contains the active ingredient testosterone undecanoate
Low levels of testosterone can promote decreased impotence, infertility sex drive, because of decreased sperm production. The other reasons are decreased physical and mental activity, fatigue, and weakening of bones (osteoporosis). Testosterone is recommended as replacement therapy when the natural testosterone level in the body is too low, causing problems mentioned above.
Natural testosterone level is likely to fall slowly with the increasing age. And it falls rapidly with the surgical removal of the testicles (testicular cancer). The natural testosterone production may also fall because of the reduced functioning of the testicles (hypogonadism or eunuchoidism) resulted by testicular disease. Or this might be due to decreased gonadotrophin production in the pituitary gland, caused by pituitary disease.
Testosterone replacement therapy allows natural testosterone levels to return to a normal level. This relieves the symptoms of T deficiency.
How Nebido is administered
Nebido injection is considered a depot injection. It is slowly injected into the muscle of the buttock and there it forms a reservoir of that product. The testosterone gradually releases over some time from the reservoir into the bloodstream.
The injection is generally given once in every 10 to 14 weeks. However, the frequency will depend on the specific testosterone levels of an individual. After the first injection, you may have to come back for another injection after six weeks. Therefore, the correct testosterone level is achieved quickly.
You can consult a doctor if you experience signs such as frequent and persistent erections, nervousness, irritability, or weight gain after starting the TRT. These signs suggest that the testosterone levels are too high and the dose needs to be adjusted.
You need to have regular blood tests so you can monitor the red blood cells, the function of the liver, and the prostate-specific antigen (PSA) level. Remember that testosterone can increase the chances of prostate cancers and enlargement of the prostate.
The health expert will perform various examinations to assure the user don’t have prostate cancer before they start TRT with Nebido. The health experts need to perform a digital rectal exam for checking the prostate gland of the users at least once a year while they are receiving TRT.
Who are not suitable candidates for Nebido?
People with the below problems shouldn’t have Nebido injections. The problems we are talking about are:
- Breast cancer.
- Primary liver cancer.
- Prostate cancer.
- Kidney disorder called nephrosis or nephrotic syndrome.
- High level of calcium in their blood (hypercalcaemia).
Nebido injection is not advisable for children, adolescents, and women. This as medicine should not be used if the users are allergic to any of its ingredients. You should inform the health expert if they have previously had such an allergy.
If you experience an allergic reaction by using this problem, you should stop using this medicine and inform the doctor or pharmacist without wasting more time.
Meanwhile, people with below-mentioned factors should use Nebido more carefully:
- Elderly people.
- People with a history of kidney or liver disease.
- Having heart disease, eg heart attack, or heart failure.
- History of high blood pressure (hypertension).
- Cancer spread from its original site to the bones (skeletal metastases).
- History of migraines.
- Sleep apnoea (when breathing temporarily stops during sleep).
Check out the Nebido injection side effects
The potential side effects can badly impact an individual’s health in different ways. Here are some side effects associated with Nebido. These side effects affect people who have been using higher doses for a prolonged time.
- Feeling sick and vomiting.
- Mood changes.
- Reaction at the injection site.
- Prostate problems, such as the growth of the prostate gland, increased PSA levels, and prostate cancer (see warning section above).
- Persistent painful erection of the penis (priapism). Tell your doctor straight away if you experience this.
- Nervousness, anxiety, or irritability.
- Change in sex drive.
- Breast pain, enlargement of the breasts.
However, here take a look at some of the brilliant advances of undergoing TRT with Nebido.
Here are the bodybuilding benefits of having TRT with Nebido
More muscle, less fat
Testosterone helps in increasing lean muscle mass. And this is great for controlling weight and increasing energy. For men suffering from testosterone deficiency, TRT can help in decreasing fat mass and increasing muscle size as well as strength. However, to mug up the benefits to the fullest, users should combine TRT with exercise and strength training (https://www.healthline.com/health/benefits-testosterone#benefits).
TRT therapy helps in increasing the muscle mass by boosting the protein synthesis procedure. It consequently fuels the nitrogen retention procedure in the muscle tissues. Thus, testosterone replacement therapy is equally popular among fitness enthusiasts as well as among people suffering from muscle wasting diseases.
Healthy cardiovascular health
A healthy heart helps in pumping the blood to the remaining parts of the body. It provides muscles and organs with the required oxygen so they can give their peak performance while doing rigid exercise. Testosterone promotes red blood cell production through the bone marrow. Low testosterone levels are associated with various cardiovascular diseases.
However, can TRT help fight heart diseases? According to the small studies, men with heart disease who went for testosterone therapy had heart improvements. Even some were able to boost their walking distance by 33%.
Another study found out that TRT widened healthy arteries. However, a more recent study of 83,000 men discovered that men who got their natural T level back were 24% less likely to experience a heart attack and 36% less likely to have a stroke.
Testosterone plays a crucial role in bone mineral density. Bone density reduces as men age and testosterone reduces. This increases the risk of weak bones and osteoporosis. Strong bones support your muscles and internal organs, which can boost athletic performance.
Research shows that bone density increases with TRT with proper treatment. TRT considerably increases the spinal and hip bone density that is a great support while doing an athletic performance. Another study on females transitioning into males showed that testosterone enhances bone mineral density.
Better verbal memory
The research reported that men with higher testosterone have a reduced occurrence of Alzheimer’s disease. Also, there is evidence for a strong connection between testosterone and cognitive abilities including verbal memory and faster processing.
Increased libido and arrogance
Testosterone levels naturally increase the sexual arousal, activity as well as arrogance that help in doing heavy exercises. Men with higher testosterone levels usually enjoy more sexual activity. Older men require more testosterone for libido and for treating erectile dysfunction.
Studies found that testosterone therapy can advance your sexual performance and health. It also reported that there is a maximum testosterone level before there’s no enhanced response. For men without hypogonadism, increasing the testosterone may not help in boosting the libido.
Reduced testosterone levels are often led by the poorer quality of life. Some symptoms of testosterone deficiency include depression, irritability, and fatigue. However, research shows that this may only be for men suffering from hypogonadism. Men with a normal testosterone decrease over time didn’t show increased depression.
The effects of TRT on mood can differ from person to person. Men with hypogonadism reported better mood and well-being, along with reduced irritability and fatigue. Research shows that TRT may also be an effective anti-depressant aid.
More about Nebido and its use
Nebido comprises testosterone that is a male hormone, as the active ingredient. Users take Nebido injections into a muscle. It is stored there temporarily and gets gradually released with the passing time. Nebido is preferred to be used in adult men for treating testosterone replacement or willing to build muscles.
It helps in the treatment of various health issues promoted by a testosterone deficiency or male hypogonadism. These need to be assured by two separate blood testosterone measurements and also comprise clinical signs such as:
- low sex drive
- bone loss caused by low hormone levels
- depressive moods
Things you need to know before taking Nebido for bodybuilding
You should not be using Nebido if:
- You have an allergy to testosterone undecanoate or any other ingredients in this steroidal health compound
- You are suffering from androgen-related cancer or suspected prostate or breast cancer
- You have or had been suffering from a liver tumour.
However, Nebido is not prescribed for women.
Precautions and warnings
You should consult a doctor before administering Nebido if you are suffering from or ever had:
- Heart, kidney
- Liver problems
- blood clotting problems
- Temporary breathing issues during sleep (apnoea) as these may get worse
- Cancer (as the calcium level in your blood should be tested regularly
- High blood pressure as testosterone can increase blood pressure)
For patients suffering from the severe liver, heart, or kidney disease, administering Nebido may promote various severe complications as water retention in the body sometimes accompanied even by heart failure (https://www.medicines.org.uk/emc/product/3873/pil). Therefore, bodybuilders willing to increase lean muscle should take this compound carefully.
How to use Nebido for bodybuilding
Nebido injections (1 ampoule/vial) should be taken very slowly into the muscle. The injections should be taken every 10 to 14 weeks. It is sufficient to maintain enough testosterone levels without leading to a testosterone build up in the blood. Nebido injections should be strictly taken as intramuscular injections. Special care should be taken for avoiding injecting this product into a blood vessel.
Beginning of the treatment
Health experts measure the level of testosterone in your blood before starting the treatment and during the early phases of the intake. They may give users the second injection after six weeks to reach the required testosterone level quickly. This depends on the symptoms and testosterone levels of the user.
Maintaining the Nebido levels at the time of the treatment
The injection interval should be 10 to 14 weeks. Health experts will measure your testosterone levels regularly at the end of an injection interval. This is how they make sure it is at the right level. If they find the level too low, the experts may decide to give injections more often.
On the other hand, if the testosterone levels are high, the experts may decide on giving injections less often. Do not miss the injection appointments. Or else, you will fail to maintain the optimum level of testosterone.
If you are using more Nebido than required
Signs of taking too much Nebido:
- Weight gain
- Long-lasting or frequent erections
If you have any of these, tell your health expert. They will inject less often or will stop treatment if necessary.
Possible side effects
Just like all steroidal health compounds used in bodybuilding, this compound can also cause side effects, even though not everybody experiences them. The most common side effects are acne and pain at the injection site. Make sure you are not taking high doses for a prolonged time.
Common side effects
- Weight put on
- Hot flushes
- Enlarged prostate and related problems
- Abnormally high red blood cell level
- Pain, bruising, or irritation at the injection site
How to store Nebido
You should keep this medicine out of the sight and reach of children. This medicinal product does not require any extraordinary storage techniques.
- You should notbe using this steroidal compound after the expiry date.
- Do notthrow away any health-enhancing elements through household waste or wastewater. Your pharmacist can help you in this regard. All these measures will help you protect the environment.
4 ml solution contains 1000 mg testosterone undecanoate as the active ingredient (corresponding to 631.5 mg testosterone). The other ingredients are benzyl benzoate and castor oil as excipients.
This compound is recommended for Testosterone replacement therapy or confirmed male hypogonadism. Also, bodybuilders use this for increasing muscle mass and cutting excess fat.
Special warnings and precautionary steps you should follow:
Nebido is not recommended for use in children, adolescents, and women. Before testosterone initiation, all intended people should undergo a detailed examination. It will help in excluding the risk of pre-existing cancer of the prostate.
Regular and careful monitoring of the prostate gland and breast should be performed. You should check the following laboratory parameters periodically: testosterone, haemoglobin, haematocrit, and liver function tests. Androgens may quicken the sub-clinical prostatic cancer progression and benign prostatic hyperplasia (https://www.nebido.com/prescribing-information).
Nebido should be used cautiously in cancer patients who are at risk of hypercalcaemia. It is recommended to do regular monitoring of serum calcium concentrations in these patients. In patients receiving testosterone replacement therapy, Benign and malignant liver tumours have been reported.
Among users suffering from ischaemic heart disease or severe cardiac, hepatic or renal insufficiency, testosterone therapy may promote severe complications featured by edema with or without congestive cardiac failure. In this case, users should stop the treatment immediately.
It is recommended to observe the limitations of using intramuscular injections in patients with acquired or inherited blood clotting irregularities. Testosterone and derivatives can increase coumarin-derived oral anticoagulant activities.
One with thrombophilia should use Nebido with caution. It is because there have been post-marketing studies and reports of thrombotic events in these patients at the time of testosterone therapy. Nebido should be taken cautiously by patients suffering from epilepsy and migraine, since the conditions may aggravate.
Athletes should know that Nebido comprises an active element that may promote a positive reaction in anti-doping tests. Androgens are not advisable for promoting muscular development in healthy people or for boosting physical ability.
Just like all oily solutions, Nebido should be injected only intramuscularly and very slowly. It might take even over two minutes. Pulmonary microembolism of oily solutions can lead to signs and symptoms such as cough, hyperhydrosis, chest pain, dizziness, dyspnoea, malaise, paraesthesia, or syncope though in rare cases.
These reactions may take place immediately after or during the injection. And these are reversible. Usually, the treatment is supportive.
Posology and procedure of administration:
Nebido needs to be injected every 10 to 14 weeks. Nebido is for intramuscular injection strictly and it should be administered very slowly. Injecting Nebido deeply into the gluteal muscle should be done carefully by following the precautions recommended for intramuscular administration.
One should avoid intravasal injection. The first injection interval can be reduced to a minimum of six weeks. Nebido is not recommended for use in children, adolescents, and women.
Testosterone Nebido – Facilitating muscle gain
If you are willing to gain muscles or you are suffering from testosterone deficiency or you have experienced the symptoms of low testosterone, you may already know about Nebido injections. It is a potential treatment procedure for dealing with this condition.
Nebido is an injection comprising testosterone, the most important hormone in the male body. In these injections, testosterone is the active ingredient, and these help in fighting the low testosterone level in the body.
How testosterone Nebido injections work
Users need to take intramuscular injections. When it is injected, it is stored within the muscles and then it gradually releases. This promotes an evenly distributed effect. And that increases the effectiveness of this compound during bodybuilding. Nebido is commonly used as a treatment method for men suffering from a lack of testosterone. This condition can be promoted by any factors.
But testosterone replacement therapy is found to be most effective when used in men experiencing low testosterone because of the natural aging process or having symptoms such as hypogonadism (https://balancemyhormones.co.uk/what-is-testosterone-nebido-and-how-to-get-it/).
There are many procedures to assure if you are suffering from low testosterone since the symptoms are pretty well-documented. Here are some of the possible symptoms of testosterone deficiency. Here are some symptoms of low testosterone:
- Low sex drive
- Muscle mass loss
- Bone density loss
If you are experiencing any of these symptoms, you may have testosterone deficiency and need treatment. One of the best ways to address this condition is to go for testosterone replacement therapy. In other words, people willing to increase muscle mass can benefit from these compounds.
How to use Nebido
If you have decided on taking Nebido for bodybuilding and as a treatment method for testosterone deficiency or a similar condition, you may want to know more about how the product is administered and how it works. The prime reason for the effectiveness and success of Nebido treatments depends on how you administer it.
To initiate the treatment, your medical professional will inject Nebido slowly into one of the muscles in your body. This is usually done in the ventrogluteals, deltoid, or any other dense muscle area. The Nebido injection is very strong. And it lasts for a while, which makes it easier to use Nebido injections than many other types of TRT injections.
What is more, the delivery procedure makes Nebido injections an effective way to increase the testosterone level in the body. The reasons behind this are that the injections are the most direct procedure to get testosterone in the bloodstream.
With a Nebido injection, the injection site becomes a natural reservoir of testosterone that slowly releases throughout the weeks. In this way, users get an evenly-balanced treatment that won’t disappear after a few days.
For properly-taken Nebido injections, you will only have to take an injection every 10 to 14 weeks. This timeframe and wide interval of two injections make it a highly aspired bodybuilding compound. In fact, this is the reason many people suffering from testosterone deficiency or willing to build muscles prefer going for this compound.
How to inject testosterone Nebido
If you are willing to know how to use testosterone Nebido, it is actually a very simple procedure. Testosterone Nebido is taken solely by injection, which is the most efficient way to administer testosterone in the bloodstream.
With a single injection, you can assure that it will be very effective on your testosterone level making it easier for you to deal with the side effects of testosterone deficiency.
Your medical professional will show you the details. But you need to know that testosterone Nebido is very easily administered with just an injection.
Things you need to know about Nebido
Nebido injections are able to help thousands of men willing to build muscles or suffering from testosterone deficiency levels across the globe. However, it may not be the best testosterone option for you. You need to consult the experts if it will be suitable for you.
There are several factors that you need to know before you decide on taking such injections as a treatment procedure for treating low testosterone. You need to know the risks, benefits, side effects, and other medical factors that will determine the decision. The factors that will determine whether Nebido injections will be a suitable investment for you are as follows:
- Nebido formulations comprise 1000 mg testosterone undecanoate in 4ml of suspension. And it is usually injected once every 10-14 weeks.
- The injection size is quite large (4ml). It is injected all at once. And it can be quite painful. A patient must be monitored for anaphylaxis after the injection.
- In most countries, Nebido needs to be administered by a health care professional. That is why users often have to schedule a clinic visit every 10-14 weeks.
- There are other types of testosterone too. If you find that the Nebido doesn’t suit you, you can try something else.
- Make sure you are buying the quality guaranteed products and are consulting the health experts. They can help you start with the right dosage according to your current health condition and other determining factors.
When Nebido is not suitable for you
There are many medical conditions that might make someone not suitable for taking Nebido injections. Considering this will protect people from harmful medical effects that might be caused if Nebido testosterone injections are taken along with other medications.
These injections might interfere with the treatment going on. Here are several factors and features that may make you not a suitable candidate for Nebido injections:
- You have allergies to testosterone or other ingredients in Nebido injections
- There is androgen-dependent cancer or breast or prostate cancer
- Have or had liver tumours in the past
Apart from that, Nebido injections are not suitable for women, children, or adolescents. And also remember that there is no advantage in using Nebido injections for men under the age of 18. People having these descriptions should not administer Nebido injections as a treatment.
Even if you start Nebido injections after consulting a doctor after determining that you are a suitable candidate, you still should monitor your health over time and check out for any side effects. It is crucial that you keep in touch with your medical professionals and notify them in case you are having any side effects.
In case you have experienced any of the following before starting or after taking Nebido injection, you should immediately contact your health expert. They will help in re-evaluating your treatment plan and determine if this testosterone replacement therapy is still the right option for you:
- Sleep apnea
- Blood clotting
- Liver disease
- Heart problems
- Kidney Disease
If you are experiencing all these signs, it can certainly affect whether Nebido injections will be a suitable option for you. Consult your medical professional immediately to assure if it is still a secure option for you to be administering Nebido injections.
Starting taking Nebido injections
Before you start taking Nebido injections, there are certain factors you and your medical expert should consider. First, your health expert will take your blood sample to measure the existing amount of testosterone and other elements in the blood. These measures will be crucial.
In the beginning, the health expert may decide on giving you the second injection after 6 weeks of treatment to enhance the effects. From that point, you may have to take injections every 10 to 14 weeks. This procedure is done fast to reach the desired testosterone level so you can enter the maintenance part of the therapy.
Maintenance of Nebido testosterone levels
The next stage in the Nebido injection treatment is to get and maintain a healthy testosterone level after the initial injections. To achieve this, you should be seeing your medical professional. He/she will be administering your treatment every 10-14 weeks so you can get the best results.
During this stage, the doctor will be taking tests and check the amount of testosterone in the blood. They will decide if there is enough testosterone in the blood during this time. They will also decide if they need to make adjustments in your dosage amount or frequency.
During the maintenance phase, you should bring up any concerns or questions you will be experiencing during the treatment phase. This will allow your medical professional to address the problems.
How to get testosterone Nebido?
- Talk to a consultant about your health symptoms.
- Get a full testosterone blood test to make sure if there are any health issues.
- After a successful diagnosis of testosterone deficiency experts will offer you various options for treatment.
- As per the preference and what experts think will work the best for you, they may prescribe you testosterone Nebido.
- Experts will issue the Testosterone Nebido prescriptions. Also, they will be monitoring your health and testosterone levels on an on-going basis.
- The other factors they will be monitoring are the symptoms and prescribed treatment of testosterone Nebido.
The possible side effects of Nebido
One of the most crucial things you should know while starting Nebido injections is that there are potential side effects. You should be familiar with these side effects since this is the best way to be able to address them if they take place. There are some common side effects that might take place while using Nebido injections and some others may be quite uncommon.
We are going to be discussing both the common and uncommon side effects. However, if you experience any side-effects you are concerned about, you should reach out to your health expert. Check out some common side effects associated with Nebido injections:
- Hot flashes
- High red blood cell count
- Weight gain
- Enlarged prostate
- Irritation at the injection site
Some of the lesser-common side effects are here:
- Allergic reactions
- Increased appetite
- Prostatic disorders
In case you experience any of the symptoms mentioned above, you need to be concerned about your health and comfort. At this point, contact your doctor immediately.
Testosterone Nebido dosages
Typically you will have to inject 1000mg every 8-12 weeks. Well, the dosage might differ from user to user. Your health expert will set the right dosage after considering all the determining factors.
Testosterone Nebido costs
Testosterone Replacement Therapy packages for testosterone Nebido cost ranges between £70 and £113 per month. It basically depends on the treatment choices you go for.
Nebido injections have been one of the most productive and commonly-used programs for bodybuilding and for men suffering from testosterone deficiency. Therefore, interested people can consult health experts if they are willing to administer Nebido.
Consulting an expert is important since they can help you learn the right dosage according to your sex, age, body weight, any medications you are taking, and other crucial factors. Remember that taking high dosages for a prolonged time can promote various unwanted side effects.
Consulting experts can help you keep side effects at bay and enjoy the benefits of the products to the fullest. The other crucial factor that users especially athletes, bodybuilding enthusiasts, and people willing to lose weight should keep in mind is that only taking the right dosage of the quality product won’t be enough.
If you want to make the most of Nebido based TRT therapy, you will have to follow a rigid exercise schedule along with following a proper diet. Once again, if you are willing to purchase the best quality products at the best rates, you should head over to a trusted online supplier. Here along with having profitable shopping deals, you will also enjoy pleasing customer services.