Peptides have gradually become more and more relevant in recent years among professional bodybuilders and fitness enthusiasts. Using peptides have become trendy because this is influenced by the comparative difficulty in administering anabolic steroids. However, do you know what these substances are? Also, you might not even know if these are really legal alternatives to steroids, right? The other common question that may be buzzing around your mind is what are the benefits of using peptides? We are going to discuss all these, especially the cutting peptides in detail, in the following passages.
What are peptides?
Well, a peptide is a short chain of amino acids. The chain generally comprises 50 or fewer amino acids with an amino carboxyl end. Peptides exist in the body naturally and also these can be synthesized artificially. Also, you can get them from the food you regularly eat.
People often mistake these compounds for proteins. And that is quite obvious. This is obviously because both of these compounds are made up of amino acids. However, this is not the right concept. These two differ from each other in terms of their particular construction. Peptides have no more than 50 amino acids, while proteins comprise more.
These tiny chains of amino acids are found in every cell of the human body. These help in the efficient production of hormones such as growth hormones that are based on proteins. Peptides come in different forms such as polymers, oligopeptides, and neuropeptides.
Why bodybuilders use peptides
Maybe, the basic reason why bodybuilders used these is to advance their growth hormone production. And this is no more hush-hush stuff how HGH helps in improving the growth of lean muscle mass. Our body utilizes peptides for promoting heightened secretion of HGH. Thus, it makes it easier to grow bigger muscle mass. Administering them will also help in enhancing strength. It is also said that peptides can boost testosterone production too.
The other reason bodybuilders administer peptides is it has the ability to recover faster. They help in making sufficient oxygen accessible to the muscle cells. These also advance the level of endurance among the users. These advantages have made them famous in the athlete community. Also, Peptides help in burning excess body fat. And this is another reason these are found highly advantages in bodybuilding (https://www.hgh.com/health/peptides-bodybuilders-use/).
Various types of peptides
There are various peptides accessible. Also, new ones are added from time to time. Different types of peptides are more suitable for particular purposes. For example – muscle building, fat burn, performance enhancement, etc.
Various types of peptides available on the market are categorized into different groups. And this is generally based on the mode in which they act. Here we are going to discuss several popular groups of peptides. So here we go.
Growth hormone-releasing hormones (GHRH)
GHRH, as the name suggests, helps in stimulating the secretion of growth hormone. The duration of secretion depends on the particular category of peptide that you are administering. A crucial point to note here is that these compounds are effective only to a certain extent. Going beyond the saturation dose, generally varying from person to person will not advance the amount of secreted HGH. Here are several peptides falling in the GHRH group.
Modified GRF (1-29) is known to be beneficial in promoting the growth of muscle and fat burning. Also available as CJC-1295 without DAC, this peptide may help in fighting the signs of aging as well. Also, it helps users sleep better. The half-life time of MOD-GRF (1-29) is a half-hour generally.
CJC 1295 DAC
This contrasts Modified GRF (1-29). CJC-1295 with DAC generally differs from the other peptides depending on how long-lasting the effects are. The half-life is about a week. And that makes it suitable for users who want to avoid the stress of using peptides frequently. The substance meets the same purposes as MOD-GRF (1-29).
HGH Fragment 176-191
This peptide, just as the name indicates is a part of the human growth hormone. It is a modified form of the amino acids 176-191 in the C-terminal section of the latter compound. Bodybuilders mainly use it for enhancing fat burning and for advanced and more noticeable muscle growth. When it comes to weight loss, HGH Fragment 176-191 is considerably more powerful than regular growth hormone. It also fights the signs of aging as the positive effects on IGF-1 levels.
Having a similar structure as CJC-1295, sermorelin is basically used for fighting the signs of aging. However, it is also beneficial for muscle build-up. It accounts for 29 amino acids of the 44 that construct growth hormone-secreting hormones. This peptide is powerful for advancing HGH levels, studies report. It was observed that the 1-29 amino acid chain mainly regulates the ability of GHRH to stimulate the release of GH by the pituitary. However, sermorelin comes with a very short half-life that is about 10 minutes or sometimes less.
Growth hormone-releasing peptides (GHRP)
These substances may be taken as an improvement on GHRH as per the ability to encourage the secretion of growth hormone. GHRP promotes the secretion of increased amounts of Growth Hormone in the body. Contrasting the case of GHRH, you will not need to look at particular times to benefit from the pulse produced in your body. The Growth hormone-secreting peptides generate growth hormone burst when you administer them. They are also accessible in various types as follows:
This is basically used for muscle building, anti-aging, and weight loss purposes. It is a potent peptide that promotes growth hormone release. Also, GHRP-6 fights inflammation and helps in boosting the rate of recovery. Several professional bodybuilders prefer using it along with steroids for greater power. The peptide not only stimulates the pituitary for the production of GH, but this also suppresses the production of somatostatin that could obstruct the release.
If GHRP-6 is potent for growth hormone release, this peptide is even stronger. GHRP-2 also has a similar use just like the other compounds. However, it does not increase the appetite as the other peptide. And this tends to make it more suitable for people willing to improve lean muscle mass. What is more, it does not numb when you take it in low doses without taking breaks as needed for other peptides.
In this compound, you have a peptide that has the potential to stimulate Growth Hormone release without promoting problems related to others. Just as GHRP-6, it both enhances the pituitary and overturns somatostatin. Although it is not the most powerful growth hormone-releasing peptide, it neither promotes your appetite to flow radically nor helps heighten your prolactin or cortisol levels. These are the reasons that make them popular among some users.
Users get even better growth hormone release from this peptide than both GHRP-2 and GHRP-6. Similar to other GHRP and GHRH peptides, it is useful for muscle growth, weight loss, and anti-aging as well. Hexarelin is even better than any other growth hormone-releasing peptides at any level of dosing. However, this means it is more potential in desensitizing, irrespective of dose, or whether breaks are taken.
Insulin-like growth factor-1 (IGF-1)
This type of peptides is taken by bodybuilders for enhancing the insulin-like growth of muscles. These compounds are beneficial for focusing on particular muscle groups. Also available as Somatomedin C, IGF-1 has become a popular peptide used for developing muscle mass. IGF-1 is also accessible in various variants.
This is a famous variant of IGF-1 that buyers will get on the market these days. IGF-1 LR3 contains 83 amino acids. That means it has an extra 13 amino acids in the chain of the standard insulin-like growth factor-1. The polypeptide has qualities that make it more potent than regular IGF-1. It has a longer half-life of up to 30 hours, in comparison to the latter’s 15 hours. Along with bodybuilding, IGF-1 LR3 helps in fat burning too. The other benefit it serves is a quicker recovery rate and slow aging.
Mechano Growth Factor (with PEG)
Also available as PEG-MGF, this peptide not only helps in promoting the growth of muscles. But, it also forms new muscle cells. The IGF-1 form is connected to polyethylene glycol (PEG). And that differentiates it from any standard Mechano growth factor. The consequence of this is that the half-life of MGF increases to days from minutes.
It is even more suitable to take PEG-MGF after workouts. It is because this is the mechano-sensitive feature of MGF. In other words, the mechanical stimulus activates it. The peptide promotes faster recovery from any damage in the muscles. The list of peptides mentioned is not all comprehensive. There are various others available on the market. Some of them may not be advantageous for bodybuilding.
How to use peptides?
These compounds come in the powder forms that you have to reconstitute with sterilized water and then take injections of it. You either have to take subcutaneous or intramuscular injections. But the former one is a more common option. This is advisable to use an insulin syringe for administering it. And remember you always need to be extra careful when you are taking self-injections of peptides. Confirm you do not strike a blood vessel.
Combining GHRH with GHRP
Using peptides doesn’t really mean you have to use one or the other. You can reduce the power and the benefit by using either GHRH or GHRP. Also, you can amplify the effects by administering both. For one, this will help to sustain the levels of somatostatin. The level of that hormone can be an issue you may have to deal with when administering only GHRH since it inhibits the growth hormone.
Along with this, when you are using both GHRH and GHRP, you need not target particular times when your body is generating pulse to gain better advantages. Remember that GHRP can create a greater GH pulse without depending on the body for that reason.
The point here to note is that how much growth hormone release is enhanced depends on the peptides you are combining. A sample combination that can offer a brilliant effect is GHRP-6 and MOD-GRF (1-29). It might need a bit of mix and match to become the right combo.
Is using peptides legal?
The legality of the product will determine the product you will use. For the purposes of research, it is absolutely all right for you to have these compounds if you require them. But when it comes to the discussion of bodybuilding, you need to be way more careful. However, in most cases, people use these for the purpose of building the body. Note that buying and using peptides for purposes other than research is illegal.
People selling these compounds add a disclaimer on the bottles that they are only for research purposes. This means you can be arrested and prosecuted if you are found administering them. That is why some users prefer speaking in coded language while discussing the usage. For example – talking about giving injections to their animals with these substances.
One considerable cause of why it is illegal to administer peptides for bodybuilding is that safety is unclear. It needs a lot of testing to determine if it is safe for the use of humans. It seems not enough research has been done to approve its use by humans.
Peptides can promote the growth of bigger muscles. These can also help you burn the excess body fat, along with improving muscle recovery and slowing down the aging process. Each type has particular purposes. These substances are beneficial in many ways since they enhance the release of GH by the pituitary gland. Growth Hormone secretion gets amplified when GHRH and GHRP compounds are used together.
Now, let’s dig into the matter of using peptides in the realm of weight loss.
Peptide therapies for weight loss
If you are in the bodybuilding regimen you might have heard of peptide therapies for weight loss. Peptides have brought many advances in the field of weight loss. You will no longer need to follow strict diets for losing weight nor you will have to spend most of the time in the gym. Peptide therapy is considerably effective in weight loss. And it is gaining popularity for its safe and assured results.
Peptides are available in various forms, some are familiar and some are unknown. Peptides can promote various benefits. And therefore, people willing to mug up health results should check them out.
Whenever it is about weight loss, the role of hormones is quite inevitable since these help in increasing the fat-burning procedure. The adjoined passages will help you learn more about peptide theory so you can have a clear idea regarding what it is, and how helpful it can be in the field of weight loss. However, let’s first make out what these substances generally are (https://valleywellnesscenter.com/2019/12/peptide-therapies-for-weight-loss/).
PEPTIDE – WHAT THESE SUBSTANCES ARE?
Peptides are a chain of amino acids. Peptides are organic substances naturally occurring in the human body. However, they can also be made artificially. When these peptide chains connect, they transform into proteins.
Many times these peptides transform into hormones sending and receiving specific information to the tissues and cells through the blood. Consequently, the body switches on and off the specific cell functions. And in fact, this specific feature of peptides makes it possible to use it in various treatments.
In other words, Peptides are mini protein. Also, you can say that these are the short-chain of proteins that consist of less than 50 amino acids. These play an important role in the development of DNA, tissues, genes, and hormones. Apart from that, these are vital for the healthy function of the pituitary gland.
Peptides, as mentioned above, are also synthesized artificially. Usually, manufacturers break down the proteins into peptides for making them easier to be absorbed in the body. These artificially made peptides are thus, a copy of natural peptides. These help in the production of testosterone and HGH. And that, in turn, helps in muscle growth, cartilage healing, and weight loss. Collagen is basically an example of a peptide that is quite difficult to absorb in the body. However, collagen peptides can be absorbed in the body readily.
WHAT IS PEPTIDE THERAPY?
Peptide therapy, just as the name indicates, utilizes peptides to introduce particular reactions in the body for healing or various therapeutic purposes. Studies report that certain types of peptides help in reducing weight since they take part in the procedure of breaking the visceral fat. Also, these actively get involved in the reduction of inflammation.
Peptides are renowned for increasing the production of HGH or Human Growth Hormone. That is why these are also used in various peptide therapies such as anti-aging, muscle mass increase, weight loss, and repair. Generally, in peptide therapy, you need to inject peptides under the skin as a subcutaneous injection. Apart from that, in several therapies, these peptides are taken as a cream, in oral form or as a nasal spray.
Peptide therapies basically, improve the communication between cells by instructing them. As a result, it improves the efficiency assuring that the body is able to absorb highly nutritious foods for stem cell regeneration and mitochondrial function.
PEPTIDES THAT ARE COMMONLY USED
There are various kinds of hormones that our body utilizes. Yes, some might be more common than others. The commonly used peptides that are used in therapies are:
- Melanotan 2
- IGF 1
However, all of these peptides mentioned above are quite similar in their fundamental purpose that is enhancing the production of GH (growth hormone). Well, here we are going to focus more on sermorelin since it is used widely in peptide therapies. After the age of 20, the HGH or human growth hormone usually starts to decline. With the help of peptide therapies, one can enjoy the heightened level of HGH or human growth hormone in the body.
Administering peptides in therapies is a less complicated, safer, and cost-effective method to use for the enhancement of HGH or human growth hormone. Also, it helps in losing weight so you can lead a productive lifestyle.
SIGNIFICANCE OF PEPTIDE THERAPIES FOR WEIGHT LOSS
The human body comprises more than 7,000 known peptides that play an important role by carrying out essential biological functions. Apart from their application in cancer treatment, dementia, heart diseases, and diabetes, these are also beneficial in safe and effective weight loss. There are several peptides that are advantageous in assisting weight loss and are also known as GH or growth hormones.
CJC 1295, Tesamorelin, Hexarelin, Ipamorelin, GHR2, and GHR6 are several names that help in losing weight. All of these help in shedding weight from the areas such as the abdomen. And that fat is referred to as visceral fat. Besides other peptides, peptide CJC 1295 and Ipamorelin help in increasing the production of growth hormones.
In peptide therapy, peptide CJC 1295 is taken as a subcutaneous injection or applied as a cream. Is there anything that can subsequently increase the GH growth hormone secreted by the anterior pituitary glands? For better results, peptide therapy users are advised to follow a healthy diet along with a healthy and routine lifestyle. That will boost the weight loss procedure. Apart from that, you can also use that along with Ipamorelin and other peptides. Thus, it will boost the internal production of GH.
Don’t forget that growth hormone is a naturally occurring hormone that is produced in both awake and the sleep cycle of a person. CJC 1295 and Ipamorelin are not hormones. These are only the peptides that give signals regarding the production of GH. Both of these compounds are endogenous.
There are various benefits of growth hormones. And these are beneficial in burning abdominal fat. As a result, you get a smaller waistline while also it improves one’s health and assures longevity. The stored abdominal fat causes inflammation in overweight people. GHs utilize the up-regulation of lipolytic pathways for burning unwanted fat.
For melting the extra fat GH enhances the procedure of lipolysis. It will be useful in boosting the skeletal muscle mass. Consequently, the lean muscle mass rate of metabolism also gets heightened. All of this will facilitate better muscular performance.
The growth hormone sends signals to the glucose receptors on each cell. Thus, it can remove insulin resistance that is the primary reason behind type II diabetes. Apart from that, growth cells also help regulate stem cells. They make it happen by facilitating cellular autograph. They also improve cell respiration since each requires its energy to regulate functions. And this procedure of cellular respiration is necessary for weight loss and longevity.
Peptide therapy for weight loss not only fuels the fat burning process. But it also promotes longevity by keeping away the chances of diseases such as heart attack, dementia, and diabetes.
Let’s check out the benefits of peptide therapy
There are various benefits one can get from using peptides. The crucial benefits are as follows:
Shed the Abdominal Fat: Peptide therapies help in melting the abdominal fat since it boosts the lipolysis procedure that is the breakdown of lipids. Consequently, it promotes safe and effective weight loss that can be up to 65 to 70 %.
Enhancing the muscle mass: Peptides contribute to boosting the production of GH or growth hormone. Besides that, it also initiates the weight-loss process along with increasing the lean muscle mass and increasing the overall muscle performance.
Removal of damaged cells: Peptide therapies also help in increasing cellular respiration. That, in turn, helps generate energy that contributes to carrying out various cellular activities. Also, it is helpful in the removal of damaged cells that improves all the cellular functions.
Longevity: Peptide therapies fuel the growth hormone or GH production. And these growth hormones play a crucial role in reducing the chances of several fatal risk factors such as dementia, heart diseases, cancer, type II diabetes, etc.
Boosts your Self-Esteem: Being overweight, in most cases, puts an individual in low self-esteem. However, by embracing peptide therapies, people can shed the unwanted weight. And ultimately, this will boost their self-esteem and will also improve their attitude towards life.
How to mug up better results out of peptide therapy for weight loss
If you want to mug up better results from using peptide therapy for weight loss, you need to follow several tips as follows:
- It is beneficial to follow a calorie-restricted and healthy diet to improve the results of peptide therapies for cutting.
- It is better to reduce sugar and starches intake.
- Make sure you have eight hours of sleep a day.
- It is also good to take protein supplements.
- It is necessary to lead a healthy lifestyle. Therefore, try to eliminate all the extra burden of stress from your life.
- Check hormone balance, especially you should keep an eye on the on androgens and thyroid hormone levels.
- It is advantageous to reduce the insulin secretion from the pancreas.
Peptides comprise amino acids and these are also known as mini proteins. Our body naturally produces them by the anterior lobe of pituitary glands. However, they can be also made artificially. And that will mimic the natural peptides. These are advantageous in weight loss. Peptides either can be injected in the body or can also be applied as a cream. Also, these can be used in oral forms. They fuel the level of growth hormones that helps in improving the cutting process.
Some of the best cutting peptides
Protein helps in the sustenance of lean muscle tissue. And this is possible even when you are going through the cutting phase. The peptides that will assist you through a weight loss process are here:
Ipamorelin, Sermorelin, CJC 1295, and Tesmorelin are some of the peptides that will evenly help in increasing the muscle mass along with burning fat over the abdomen or visceral fat.
CJC-1295 – This compound made up of 30 amino acids is a synthetic GHRH (growth hormone-releasing hormone) analog. It is highly effective in increasing growth hormone secretion and IGF-1. It doesn’t negatively impact the pulsatility of GH secretion.
CJC 1295/Ipamorelin – This substance along with Ipamorelin is a blend that is commonly prescribed since it offers a synergistic effect. That means it can generate five times the advantages of administering the CJC 1295 or Ipamorelin alone. This substance blend promotes a maximized release of GH since the CJC 1295 and Ipamorelin come with different mechanisms of action. Also, these work on different receptors (GHRH-R & Ghrelin-R).
Together, these peptides can generate similar advances in growth hormone secretion. However, it won’t stimulate the appetite and won’t increase cortisol, acetylcholine, prolactin, and aldosterone that are seen with other peptides in its category. This combination is the most suitable for patients willing to lose fat and get lean muscle mass (https://www.peptidepracticesofamerica.com/weight-loss/).
Ipamorelin – It helps in stimulating the releases of GH (growth hormones) in a process that imitates the natural process of your body. And that sets it apart from other GH peptides used in a cutting phase. Stimulation is more selective. That is why patients can experience more advantages especially along with a healthy diet and regular-basic exercise routine. When you assure all these, Ipamorelin can produce health benefits as follows:
- Cutting: Ipamorelin enhances the level of growth hormone required for lipolysis.
- Lean Muscle Mass increase: Ipamorelin boosts the lean muscle mass of your body. Thus, it helps you get stronger and toned. Boost in the muscle mass also advances your metabolism, letting you lose weight in a quicker process.
- Anti-aging:Ipamorelin stimulates the liver so it can produce IGF-1. It helps in creating more muscle tissues. And this also regenerates the bone tissues. Strong connective tissues, bones, joints help in preventing fracture and physical wear. This GH peptide also contributes to improving sleep, mood, energy, body composition, and immune function.
CJC 1295 and Ipamorelin are not the synthetic hormones and anabolic steroids that bodybuilders use. These compounds are messaging peptides that the body produces naturally to control and maximize longevity and health. Similar to other growth hormone peptides, Ipamorelin advances the growth hormone-releasing hormone (GHRH) production in the body.
This in turn fuels the pituitary gland to increase the output of human growth hormone. With enhanced growth hormones, patients can lose weight in a faster process while it will also increase the lean muscle mass along with slowing down the aging process.
Sermorelin – Sermorelin is a bioidentical hormone that imitates the natural HGH releasing peptide produced by the brain. It is also known as a “secretagogue” since it boosts the natural hormone secretion – HGH, in this case. As a result, it promotes a more physiologic increase in HGH. And that does not let overdosing happen or never lead to HGH resistance.
Sermorelin enhances both endurance and energy. And thus, it helps in eliminating unwanted fat from the body through lipolysis. It revives the function of the cardiovascular system. Also, it leads to a more restful non-Rapid Eye Movement sleep of the slow-wave variety. It boosts the immunity system too.
Well, this is not the end. It boosts the cut and mass of lean muscle on the bones. Sermorelin also helps in reducing the glucose intake by the liver along with considerably elevating the amount of synthesized protein within the muscles. It contributes to homeostasis in the production of bodily energy fuel while it assists in stimulating the growth of organs too.
Sermorelin significantly contributes to the sustenance and function of the islets in the pancreas. Sermorelin therapy encourages kidney functions. At the same time, brain memory is improved as well. Patients suffering from high blood pressure can benefit from a healthier level of blood pressure.
It boosts the function of the immune system while some patients suffering from balding also reported that they experienced regrowth of hair. The anti-aging benefits it promotes are smoother, firmer, wrinkle-free skin. And, as far as sexual health is concerned, it increases libido, sexual function, pleasure, and performance.
Tesamorelin – Tesamorelin is basically a growth hormone-releasing hormone analog. It binds as well as encourages human GHRH receptors with identical power as endogenous GHRH. It has various other advantages such as nootropic effects and reduction of triglycerides. Tesamorelin doesn’t notably affect other pituitary hormones and their respective functions.
In recent studies, Tesamorelin has been shown to burn unwanted visceral fat. Along with that, it also improves cognitive function. That is why it can be beneficial for people with mild cognitive impairment and are at an increased risk of Alzheimer’s disease.
AOD 9604 – AOD 9604 is an advanced form of amino acids 176-191 of the GH polypeptide. It has been discovered that the fat-cutting effects of GH seem to be controlled by a small area close to one end of the GH molecule. And it seems to have no effect on insulin resistance. It acts by imitating the natural Growth Hormone that regulates metabolism. However, it doesn’t leave a negative impact on growth or blood sugar. AOD 9604 encourages lipolysis and prevents lipogenesis.
The other peptides that help in weight loss are Amlexanox, Tesofensine, IGF-1, etc. However, if you want to have peptides for weight loss, you must consult an expert first. As you have seen before that different cutting peptides can have different impacts on health, it will always be safe than sorry. Health experts can help you choose the right product and will advise you to follow the right dosage according to your health, fitness goal, and other relevant factors.