Masteron, also known as Drostanolone Propionate, is one of the most popular anabolic androgenic steroids available on the market. It is highly-valued in the bodybuilding community. It is an oil-based steroid derived from Dihydrotestosterone (DHT). It makes this steroid of the DHT-derived family of anabolic steroid derivatives.
This steroid was first developed by Syntex in 1959. However, it was first introduced to the market in the early 1970s. The manufacturer (Syntex) would also provide this steroid under various brand names, including Masteril, Metormon, Drolban, etc.
As a therapeutic agent, it was used to treat advanced inoperable breast cancer in postmenopausal women. This anabolic androgenic medication enjoyed almost 2 decades of success in it. However, it soon became extremely popular in competitive bodybuilding cycles. Many bodybuilders consider it essential when preparing for a competition.
However, in this blog, we are going to discuss what’s so great about Masteron and whether it is worth it. We will tell you everything you need to know about this steroid. Later, we will also talk about the variants of Masteron (Masteron Propionate and Masteron Enanthate). So, let’s dive right in.
Name: Drostanolone Propionate
Type: Small Molecule
Synonyms: 17β-Hydroxy-2α-methyl-5α-
Other Brands: Drolban, Masteril, Masteron
Weight: Average – 360.538
Monoisotopic – 360.266445019
Chemical Formula: C23H36O3
IUPAC Name: (1S,3aS,3bR,5aS,8R,9aS,9bS,
Pharmacodynamics: Drostanolone is a synthetic androgen. It is similar to Testosterone. It works by binding to androgen receptors. This is what causes Drostanolone to interact with the areas of the cell involved in the production of proteins. It may cause a boost in the synthesis of some proteins and a drop in the synthesis of others. These proteins have different effects that include blocking the growth of breast cancer cells, increasing red blood cell production, stimulating cells that cause male sexual characteristics, etc.
Mechanism of Action: This anabolic steroid is five times as powerful as natural Methyltestosterone. Like other androgenic hormones, it binds to the androgen receptor, which ultimately causes retention of nitrogen, phosphorus, and potassium. It also results in an increase in protein anabolism and a decrease in amino acid catabolism.
Toxicity: The most common side effects of Drostanolone Propionate include acne, virilization, hypercalcemia, etc.
Description: It belongs to the class of organic compounds known as steroid esters. It contains a steroid moiety that bears a carboxylic acid ester group.
Super Class: Lipids and lipid-like molecules
Class: Steroids and steroid derivatives
Sub Class: Steroid esters
Molecular Framework: Aliphatic homopolycyclic compounds
Substituents: Steroid ester / Androgen-skeleton / Androstane-skeleton / 3-oxosteroid / 3-oxo-5-alpha-steroid / Oxosteroid / Cyclic ketone / Carboxylic acid ester / Ketone / Carboxylic acid derivative
For more information, please visit – https://www.drugbank.ca/drugs/
Masteron is a DHT-derived anabolic steroid. It has been structurally altered by adding a methyl group at the carbon 2 position. This modification is responsible for protecting the hormone from the metabolic breakdown by an enzyme (3-hydroxysteroid dehydrogenase enzyme) found in the skeletal muscle. This structural alteration creates Drostanolone. Also, a short Propionate ester is attached to control the release time of the hormone. You can also find the Enanthate version of the Drostanolone. But it is rare compared to drostanolone Propionate. Most of the Masteron products you will find on the market are the Propionate version.
Masteron is an anabolic steroid that has powerful anti-estrogenic properties. It can help one deal with the estrogen-related problems by acting as an anti-estrogen in the body. It is actually the reason why it was used to treat breast cancer. In fact, it has been found that the use of Masteron together with Nolvadex is more effective than chemotherapy when it comes to treating inoperable breast cancer in women.
Masteron can provide hardening effects. That’s why most bodybuilders prefer to use it during cutting phases. DHT is five times more androgenic than Testosterone. Also, it has a much stronger binding affinity to the androgen receptor. It contributes to promoting a harder look. It can also enhance fat loss. You can find this steroid in cutting plans among most performance athletes. However, it can cause a significant increase in strength.
Masteron retains some of the same characteristics as DHT. This steroid doesn’t interact with the aromatase enzyme. This enzyme plays the most crucial role in the conversion of androgens into estrogen. This is the reason why Masteron doesn’t carry any estrogenic side effects at any dose. So, you don’t need to be worried about problems like water retention, bloating, elevated blood pressure, fat gain, gynecomastia, etc. It means users will experience quality mass gains without unwanted water weight gain. This is why many competitive bodybuilders use it as a cutting steroid for contest preparation and cutting phases.
The use of Masteron during the cutting phase ensures that the physique appears leaner and harder. The anti-estrogenic properties of this steroid help enhance the overall look. Masteron can also benefit the athletes looking to achieve a stronger and powerful physique. The user can also experience a slight improvement in endurance and recovery.
Masteron can also be used during bulking phases. However, it can’t provide you with significant mass gains. Most users include this steroid in their bulking plans due to its anti-estrogenic and fat loss effects. The fat loss effect of Masteron ensures that there occurs minimal fat gain during the bulking phase. And the anti-estrogenic property of this steroid helps deal with the aromatase activity due to high doses of Testosterone.
Masteron is one of those steroids that is rarely used as a base steroid in a steroid cycle. During bulking phases, it is usually stacked with Testosterone or Trenbolone. In a cutting cycle, you can stack Masteron with any steroid that helps protect lean muscle mass.
Here are some of the results that you can expect from the use of Masteron:
As mentioned earlier, Masteron has anti-estrogenic effects. Many bodybuilders use it during the bulking phase to manage the estrogenic side effects. This steroid acts pretty much like SERM. It helps prevent gynecomastia and water retention.
Masteron can provide you with a contest prep look. It will give you a detailed cut look. The fact that Masteron decreases water retention and bloating helps the muscles to feel tight. It can give you amazing muscle pumps with your physical workout.
By using Masteron, you can experience significant strength gains. You will be able to lift heavier loads of weight.
Masteron can help improve recovery times.
Masteron can also contribute to improving your mental well-being and boosting your libido.
Masteron use can cause many side effects. However, most of the side effects are well-tolerated by most men. Female users can experience virilization symptoms. Nevertheless, they can be managed with the right plan. Consider going through sections below to know about the side effects in detail.
Masteron is one of those few anabolic steroids that do not aromatize. Thus, estrogen-related side effects are impossible with this steroid. This means you don’t need to be worried about problems like the enlargement of breast tissues in men, water retention, high blood pressure, etc. Since Masteron has anti-estrogenic effects, there is no need to use an anti-estrogen due to the use of this steroid. However, you may need to use anti-estrogens depending on the specific steroid cycle that’s implemented.
Masteron use can cause androgenic side effects that include acne, accelerated hair loss, body hair growth, etc. However, the level of total androgenic activity of this hormone is not as potent as its parent hormone DHT. However, the severity of the androgenic side effects of this steroid can vary from person to person depending on individual sensitivity. For example, this steroid can significantly enhance male pattern baldness in those who are sensitive to it.
Women can experience virilization symptoms that include body hair growth, a deepening of the voice, clitoral enlargement, etc. These symptoms have been well-noted in the treatment plans of breast cancer. However, it is usually because of the high doses used for the treatment of such a condition. It means these symptoms can be managed with a low dose. If you notice any of the symptoms, discontinue use immediately.
Masteron use can cause an increase in LDL cholesterol. It can also decrease HDL cholesterol levels in the body. The effect will not be as powerful as often found in C17-alpha-alkylated steroids. This steroid could also negatively impact blood pressure.
The fact that this steroid can have a notable effect on cholesterol makes cholesterol management imperative with this steroid. If you already suffer from high cholesterol, it’s better not to use Masteron. Even if you are healthy and have no cholesterol issue, it’s important that you maintain a cholesterol-friendly lifestyle when using this steroid. Not only should you maintain a healthy diet, but you should also do plenty of cardiovascular activity every day.
There are several studies done to investigate the effects of anabolic steroid administration on heart structure and function in athletes and bodybuilders. “Prospective echocardiographic assessment of androgenic-anabolic steroids effects on cardiac structure and function in strength athletes” (https://www.ncbi.nlm.nih.gov/
In the first study, the effects of anabolic-androgenic steroids in 17 male strength athletes. They were all aged between 24-38. They self-administered the steroid for 8 or 12-16 weeks. The effects were also assessed in 15 non-using strength athletes in a non-blinded design. In the second study, the effects of Nandrolone Decanoate were investigated in 16 bodybuilders in a randomized double mind, placebo-controlled design. In the first study, the eight weeks steroid administration did not cause any significant changes in the blood pressure level or cardiac size and function. In the second study, the eight-week Nandrolone Decanoate administration did not induce significant alterations in blood pressure and heart function.
Masteron use can cause the suppression of natural testosterone production. This makes an exogenous testosterone therapy crucial when using Masteron. Otherwise, it could lead to a low testosterone condition that comes with several possible symptoms.
It’s recommended that you implement a PCT (Post Cycle Therapy) plan once the steroid use is discontinued. It will help you deal with the slow recovery of the natural Testosterone levels in the body. It will speed the recovery process and ensure that your body has enough Testosterone to carry out bodily functions properly.
Masteron will cause no harm to your liver.
A study “Gym and tonic: a profile of 100 male steroid users” (https://www.ncbi.nlm.nih.gov/
The users combined different compounds to achieve steroid doses ranged from 250-3200mg per week. Injectable and oral steroids were administered in cycles lasting 4-12 weeks. The study showed that physical problems such as skeletal muscle hypertrophy, acne, striae, etc, are among the frequent physical signs associated with steroid use.
The most common dosage of Masteron for adult men falls in the 300-400mg/week range. The 200mg per week mark is commonly utilized by bodybuilders for pre-contest preparation. Most users prefer to take an injection of 100mg every other day. Some users split the dosage into a daily injection schedule. The duration of use can be anywhere between 6 and 8 weeks. However, the duration doesn’t represent the total cycle. It is just the duration of Masteron use in a steroid cycle. If you are looking to use Drostanolone Enanthate, then you can consider injecting 1-2 injections per week.
Female athletes should take 50mg per week for a total period of 8-12 weeks. The 50-100mg per week range should be controllable for most female users. However, doses over 100mg per week are more likely to produce virilization symptoms.
In the therapeutic field, the standard dosage of Masteron is 100mg three times per week for 8-12 weeks for the treatment of breast cancer. It often leads to virilization symptoms that are irreversible in most cases.
The results of your Masteron cycle will depend on what other steroids you stack your Masteron with. Some popular stacks used by professional bodybuilders and athletes include:
A beginner or first-time user can consider stacking Masteron with Testosterone Cypionate, Anavar, and Arimidex.
Intermediate users can stack Masteron with Testosterone Propionate, Trenbolone, Winstrol, and Arimidex.
Experienced or advanced users often stack Masteron with Testosterone Enanthate, Testosterone Propionate, Deca Durabolin, Trenbolone Acetate, Winstrol, HGH, and Arimidex.
The two variants of Masteron:
Masteron Propionate
Masteron Enanthate
The main difference between these two variants is the half-life and dosage administration. Masteron Propionate works fast and needs to be administered every day or every other day. On the other hand, Masteron Enanthate is administered once or twice a week.
Beginners and first-time users can take 50-100mg of Masteron Propionate per day together with 30-40mg of methandrostenolone daily for six weeks. It will contribute to the improvement of your power performance. You will be able to attain a competitive physique without unwanted weight gain. Since Masteron has anti-estrogenic effects, there is no need to introduce another anti-estrogen or aromatase inhibitor to counter the estrogen-related effects of Testosterone. However, you need to know that this steroid doesn’t exhibit powerful inhibitor effects compared to other inhibitors such as Arimidex, Letrozole, etc.
The intermediate Masteron Propionate cycles usually last for 10 weeks. The user can take 100mg Testosterone Propionate per week (or 25mg per day) together with 400mg of Masteron Propionate weekly. The user should also administer 50-70mg of Anavar from week one to week eight. The intermediate Masteron cycle is intended for cutting and hardening of the physique. It also aids fat loss. What’s more, you will experience lean mass gains. Testosterone is included in the plan to ensure that the required amount of Testosterone is present in the body since the natural testosterone production is suppressed by the use of steroids. Masteron and Anavar will promote lean mass gains without water retention.
Advanced Masteron Propionate cycles usually last for 10 weeks. You can consider administering 400mg Masteron Propionate/week in combination with 100mg Testosterone Propionate per week and 400mg Trenbolone per week. This stack is designed for experienced users who possess comprehensive knowledge about steroids and their uses. This plan is beneficial for those who are looking to harden their physique during a cutting phase or for contest preparation. The user will also experience strength and lean mass gains. As long as you maintain a proper diet and train hard, this stack will help you notice significant changes in your physical appearance. Trenbolone is one of the potent steroids that do not convert into estrogen. Thus, by combining it with Masteron, you can expect to achieve a competitive physique within a short space of time.
However, it’s important to know that using Masteron Propionate as the only steroid in a steroid cycle will not give you the desired results. That’s why it’s recommended that you stack it with other anabolic steroids. However, higher doses do not always mean better results. In can increase the possibility of side effects. A combination of Masteron Propionate and Testosterone is the perfect choice when it comes to building up lean muscle mass. Those who are looking to gain strength during cutting phases will definitely benefit from Masteron Propionate Cycles.
Underground labs like Biomex, Geneza, etc. currently supply this product in large quantities. You can buy it online without a prescription. However, you must do some background checks prior to placing the order.
Masteron Enanthate or Drostanolone Enanthate is another variant of Masteron. It is a long ester while Masteron Propionate has a short ester. The difference between these two esters is similar to that of Testosterone Enanthate and Testosterone Propionate. Due to the Enanthate ester that is affixed on the 17-beta-hydroxyl group, the half-life of this steroid is extended to about 7-10 days. Masteron Enanthate is difficult to find compared to Masteron Propionate.
As mentioned earlier, Masteron Enanthate is a long ester. This steroid is best used over longer cycle lengths such as 10-12 week cycles. Those who are looking to achieve the hardening of the physique for a contest or competition will benefit from the use of this steroid. The effects of Masteron Enanthate can vary from person to person. It means while one user may achieve the desired results, it might have zero effects on another user. Also, it might not provide a satisfying outcome when used alone in a steroid cycle. That’s why it’s recommended that you use it in combination with other anabolic steroids.
For first-time users and beginners, the standard dosage of Masteron Enanthate is 400mg per week. However, dosages can vary depending on what the user intends to gain from the use of the steroid. Professional and competitive bodybuilders who use it for contest preparation prefer administering 200mg Masteron Enanthate weekly in combination with other steroidal compounds. With the 200mg/week dose, the users with low body fat percentage can experience significant aesthetic benefits.
However, many experienced users administer higher dosages of Masteron Enanthate (more than 600mg per week) to gain more size and strength. Nevertheless, increasing the dosage doesn’t always mean that you will achieve better results with it.
A combination of Masteron Enanthate and Testosterone Enanthate is one of the perfect stacks that can help you attain your bodybuilding goals fast. The main reason why this combination is a perfect choice is that a stack of two Enanthate esters makes timing and injection much more convenient. You can also include Trenbolone Enanthate in the plan. Trenbolone can enhance the aesthetic effects of Masteron on the body. The combination of Drostanolone Enanthate, Testosterone, and Trenbolone can help you achieve a contest prep look in a short space of time. The best thing is that neither Masteron nor Trenbolone converts into estrogen. Thus, by combining these steroids, you can expect to achieve your desired physique without unwanted fat gains. However, Masteron Enanthate is not the best choice for strength and bulking cycle stacks.
Competitive bodybuilders usually use this steroid at the final stage when they prepare for a contest. This steroid helps the user get rid of their remaining stubborn fat. However, individuals with a high body fat percentage may not see noticeable results.
Most users prefer administering Masteron Enanthate because of its aesthetic effects. It can also boost individual strength. Masteron Enanthate can also promote muscular endurance and improve recovery times.
It’s advised that you stack Masteron Enanthate with other anabolic steroids such as Testosterone to achieve your desired results. Masteron suppresses the production of natural testosterone in the body. That’s why it’s important that you include external Testosterone in your plan. It will help your system function normally. Failure to include Testosterone in the stack can cause low testosterone levels in the body. Masteron Enanthate has a longer half-life than the other variant of Masteron (Masteron Propionate). Therefore, it remains in the system for a longer period.
Beginners can start with a weekly dosage of 400mg Masteron Enanthate together with 300-500mg Testosterone Enanthate. The Testosterone dose depends on individual preferences. Any dose should be fine as long as it lies between the 300-500mg range. You don’t need to use an AI or aromatase inhibitor since Masteron itself is an inhibitor.
However, if you are thinking of stacking Masteron Enanthate with strong aromatizing compounds, then you should consider including a stronger AI such as Arimidex, Letrozole, Aromasin, etc. in the plan. Otherwise, you may experience water retention and gynecomastia.
Nowadays, Masteron Enanthate is only produced by underground labs. You can find this steroid in online steroid stores. However, before you order Masteron Enanthate online, it’s important that you do a background check. Otherwise, you might end up purchasing fake substances.
The Propionate version of Masteron is approved for medical use. This variant of Masteron is extremely popular among bodybuilders and athletes. On the other hand, Masteron is only produced by underground labs and is an illegal laboratory product.
The half-life of Masteron Propionate is 2.5 fays whereas the Enanthate version features a half-life of 7-10 days. Masteron Propionate needs to be administered daily (50-150mg injections per day). On the other hand, you can administer Masteron Enanthate once or twice a week. For example, you can administer a 200mg Masteron Enanthate injection on Monday and another on Thursday. It will help you maintain a stable blood plasma level.
The main reason why there is a difference in dosage is that the Propionate variant of Masteron clears the body faster than the Enanthate version. Masteron Enanthate stays in the system for a much longer period of time. However, whatever option you choose, you must stack it with other similar compounds to achieve a satisfying outcome.
When it comes to choosing a steroid to stack with Masteron, it’s important that you select a compound featuring properties similar to that of Masteron. If you choose a compound that offers similar end results, you can achieve your desired results much faster.
Many bodybuilders use Masteron Propionate combined with Masteron Enanthate. However, you should consider including an aromatize inhibitor when stacking either of the Masteron variants with strong aromatizing steroid compounds.
You should include Testosterone in your Masteron stack in order to deal with suppressed natural testosterone production that occurs due to Masteron use.
The anabolic/androgenic ratio of Masteron is 62:25. It means when used alone, it is less powerful than Testosterone that features an anabolic/androgenic ratio of 100:100. This is the reason why it’s advised that you use Masteron in combination with other steroids. It will increase the effectiveness of this compound.
If you are looking to use Masteron Propionate, then you can consider stacking it with other shorter esters that include Testosterone Propionate, Nandrolone Phenylpropionate, Trenbolone Acetate, etc. Similarly, Masteron Enanthate should be stacked with similar compounds such as Testosterone Enanthate, Nandrolone Decanoate, etc.
Both Masteron Propionate and Masteron Enanthate can be used as a cutting agent. They offer similar end results. However, many bodybuilders prefer to use Masteron Propionate because it has a shorter recovery time. The side effects caused by Masteron Propionate usually fade away quickly. Masteron Enanthate, on the other hand, has a longer recovery time. This is the reason why the side effects of Masteron Enanthate persist longer.
However, Masteron is best used for cutting towards the end of a contest preparation cycle. This is the time when the user usually has a low body fat percentage. Using Masteron at this stage will help you get noticeable results. Rest assured, you will achieve a more hardened physique.
As I said earlier, Masteron is not an ideal bulking steroid. Nevertheless, both Masteron variants (Masteron Enanthate and Masteron Propionate) can cause an increase in strength. They can also help the user experience lean mass gains. However, if your ultimate goal is to add size, then Masteron might not be a perfect choice.
Many users include Masteron in their bulking plans to manage unwanted fat gains. It can also boost energy and improve recovery times. What’s more, it can help you maintain the required weight even when you are on a calorie-restricted diet.
Masteron Propionate is more popular among bodybuilders, athletes, and other users than Masteron Enanthate. However, when it comes to effects, there is a very small difference between these two. The Propionate version of Masteron can be used by both male and female users. They can use it during both the bulking and cutting phases. If you follow the right dose and choose a good plan, chances are that you will be able to manage the side effects.
However, female users are discouraged to include Masteron Enanthate in their stacks. It is because this steroid has a longer half-life and takes more time than Masteron Propionate to clear the system. Thus, high doses of Masteron Enanthate could cause irreversible virilization side effects.
Another difference between these two variants of Masteron is that Masteron Propionate acts very fast whereas the Enanthate version works slowly. That’s why Masteron Propionate is administered daily whereas Masteron Enanthate is injected once or twice a week.
Both the Masteron variants have anti-estrogenic effects. Neither Masteron Enanthate nor Masteron Propionate converts into estrogen. In fact, they prevent Testosterone from converting into estrogen. It ensures that a normal level of free Testosterone is maintained.
Professional bodybuilders and athletes can experience the effects of Masteron within a short period of use. It causes a boost in energy levels and helps gain lean muscle mass while maintaining the required body weight.
There are many steroid users who do not implement a PCT plan upon completion of their steroid cycle. But implementing a PCT or Post-Cycle-Therapy plan is crucial. It can help you avoid the negative effects of steroids.
Masteron doesn’t convert to estrogen. That’s why using Nolvadex following your cycle should be sufficient. You can take 40mg Nolvadex per day for 4 weeks.
So, here’s all you need to know about Masteron. It is really one of the best cutting steroids that you can use to get leaner before a contest or competition. The right stack can help you achieve a perfect physique within a short space of time. The best thing about this steroid is that it doesn’t aromatize. Thus, estrogenic side effects are not a concern when using this steroid. So, Masteron is definitely worth buying.
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